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KMID : 0363220120500080734
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Korean Journal of Dermatology
2012 Volume.50 No. 8 p.734 ~ p.737
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Palisaded Encapsulated Neuroma with Unusual Clinical Features: 1 Case
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Cho Soo-Ick
Kim Jin-Hye
Chung Bo-Young
Kim Jeong-Won
Kim Hye-One
Park Cheon-Wook
Lee Cheol-Heon
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Abstract
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Palisaded encapsulated neuroma (PEN) is a rare, benign, cutaneous nerve sheath tumor, which usually appears as a solitary asymptomatic skin-colored papule, which usually affects the face of middle-aged adults. Here, we report a case of PEN with unusual clinical features in a 23-year-old female, developed on the back, accompanied with pain sensation. Histopathologically, it appeared as a well-circumscribed, encapsulated round nodule, consisted of uniform, broad, and interlacing fascicles of the spindle cells in the dermis. On immunohistochemical staining, the tumor cells of nodule were positive for S-100 protein and neural filaments, while the capsule of the nodule was focally positive for the epithelial membrane antigen.
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KEYWORD
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Back, Pain, Palisaded encapsulated neuroma
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